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1

INNOVATION IN THE PHARMACEUTICAL INDUSTRY: NEW ESTIMATES OF R&D COSTS

DiMasi, Joseph A., Grabowski, Henry G., Hansen, Ronald W.

Journal:

Journal of Health Economics

Year:

2016

Language:

english

File:

PDF, 389 KB

english, 2016

2

The price of innovation: new estimates of drug development costs

Joseph A DiMasi, Ronald W Hansen, Henry G Grabowski

Journal:

Journal of Health Economics

Year:

2003

Language:

english

File:

PDF, 283 KB

english, 2003

3

R&D Costs, Innovative Output and Firm Size in the Pharmaceutical Industry

Dimasi, Joseph A., Grabowski, Henry G., Vernon, John

Journal:

International Journal of the Economics of Business

Year:

1995

Language:

english

File:

PDF, 951 KB

english, 1995

4

Generic Competition in the US Pharmaceutical Industry

Saha, Atanu, Grabowski, Henry, Birnbaum, Howard, Greenberg, Paul, Bizan, Oded

Journal:

International Journal of the Economics of Business

Year:

2006

Language:

english

File:

PDF, 146 KB

english, 2006

5

Research and Development Costs for New Drugs by Therapeutic Category

Dr Joseph A. DiMasi,Ronald W. Hansen,Henry C. Grabowski…

Journal:

PharmacoEconomics

Year:

1995

Language:

english

File:

PDF, 5.09 MB

english, 1995

6

Innovation and Structural Change in Pharmaceuticals and Biotechnology

GRABOWSKI, HENRY, VERNON, JOHN

Journal:

Industrial and Corporate Change

Year:

1994

Language:

english

File:

PDF, 687 KB

english, 1994

7

Extraordinary claims require extraordinary evidence

Joseph A. DiMasi, Ronald W. Hansen, Henry G. Grabowski

Journal:

Journal of Health Economics

Year:

2005

Language:

english

File:

PDF, 87 KB

english, 2005

8

Returns on Research and Development for 1990s New Drug Introductions

Grabowski, Henry, Vernon, John, DiMasi, Joseph A.

Journal:

PharmacoEconomics

Year:

2002

Language:

english

File:

PDF, 220 KB

english, 2002

9

Demand Shifting, Optimal Firm Growth, and Rule-of-Thumb Decision Making

Henry G. Grabowski

Journal:

Quarterly Journal of Economics

Year:

1970

Language:

english

File:

PDF, 505 KB

english, 1970

10

Deposition and Long-Shore Transport of Dredge Spoils to Nourish Beaches: Impacts on Benthic Infauna of an Ebb-Tidal Delta

Bishop, Melanie J., Peterson, Charles H., Summerson, Henry C., Lenihan, Hunter S., Grabowski, Jonathan H.

Journal:

Journal of Coastal Research

Year:

2006

Language:

english

File:

PDF, 1.08 MB

english, 2006

11

The Evolution of the Pharmaceutical Industry Over the Past 50 Years: A Personal Reflection

Grabowski, Henry

Journal:

International Journal of the Economics of Business

Year:

2011

Language:

english

File:

PDF, 185 KB

english, 2011

12

The Cost of Drug Development

DiMasi, Joseph A., Grabowski, Henry G., Hansen, Ronald W.

Journal:

New England Journal of Medicine

Year:

2015

Language:

english

File:

PDF, 304 KB

english, 2015

13

Life-Cycle Effects on Corporate Returns on Retentions

Grabowski, Henry G., Mueller, Dennis C.

Journal:

Review of Economics and Statistics

Year:

1975

Language:

english

File:

PDF, 366 KB

english, 1975

14

Osteoradionecrosis of the Anterior Cranium

Ness, John A., Chang, Henry S., Grabowski, Carol M., Marentette, Lawrence J.

Journal:

Year:

1996

Language:

english

File:

PDF, 972 KB

english, 1996

15

Deposition and Long-Shore Transport of Dredge Spoils to Nourish Beaches: Impacts on Benthic Infauna of an Ebb-Tidal Delta

Melanie J. Bishop, Charles H. Peterson, Henry C. Summerson, Hunter S. Lenihan and Jonathan H. Grabowski

Journal:

Journal of Coastal Research

Year:

2006

Language:

english

File:

PDF, 1.45 MB

english, 2006

16

Economic and Policy Issues in the Pharmaceutical Industry || The Cost of Biopharmaceutical R&D: Is Biotech Different?

Joseph A. DiMasi and Henry G. Grabowski

Journal:

Managerial and Decision Economics

Year:

2007

Language:

english

File:

PDF, 2.07 MB

english, 2007

17

The cost of biopharmaceutical R&D: is biotech different?

Joseph A. DiMasi, Henry G. Grabowski

Journal:

Managerial and Decision Economics

Year:

2007

Language:

english

File:

PDF, 160 KB

english, 2007

18

Generic competition and market exclusivity periods in pharmaceuticals

Henry G. Grabowski, Margaret Kyle

Journal:

Managerial and Decision Economics

Year:

2007

Language:

english

File:

PDF, 170 KB

english, 2007

19

Entry and competition in generic biologics

Henry G. Grabowski, David B. Ridley, Kevin A. Schulman

Journal:

Managerial and Decision Economics

Year:

2007

Language:

english

File:

PDF, 189 KB

english, 2007

20

Setting the record straight on setting the record straight: Response to the Light and Warburton rejoinder

Joseph A. DiMasi, Ronald W. Hansen, Henry G. Grabowski

Journal:

Journal of Health Economics

Year:

2005

Language:

english

File:

PDF, 57 KB

english, 2005

21

Determinants and Distributional Aspects of Enrollment in U.S. Higher Education

Arthur J. Corazzini, Dennis J. Dugan and Henry G. Grabowski

Journal:

The Journal of Human Resources

Year:

1972

Language:

english

File:

PDF, 610 KB

english, 1972

22

Pioneers, Imitators, and Generics--A Simulation Model of Schumpeterian Competition

Henry G. Grabowski and John M. Vernon

Journal:

Quarterly Journal of Economics

Year:

1987

Language:

english

File:

PDF, 2.41 MB

english, 1987

23

Regulation and Innovation || Substitution Laws and Innovation in the Pharmaceutical Industry

Henry G. Grabowski and John M. Vernon

Journal:

Law and Contemporary Problems

Year:

1979

Language:

english

File:

PDF, 2.22 MB

english, 1979

24

[IEEE MILCOM 2009 - 2009 IEEE Military Communications Conference - Boston, MA, USA (2009.10.18-2009.10.21)] MILCOM 2009 - 2009 IEEE Military Communications Conference - RF communication data model for satellite networks

Beering, David R., Tseng, Shirley, Hayden, Jeffrey L., Corder, Aaron, Teng Ooi,, Elwell, Daniel, Grabowski, Henry, Frederic, Ryan, Franks, Jason, Fish, Ronald, Johnson, Austin M, Gavin, Nicholas E.

Year:

2009

Language:

english

File:

PDF, 756 KB

english, 2009

25

Analysis of Neglected Tropical Disease Drug and Vaccine Development Pipelines to Predict Issuance of FDA Priority Review Vouchers over the Next Decade

Stefanakis, Rianna, Robertson, Andrew S., Ponder, Elizabeth L., Moree, Melinda, Grabowski, Henry

Journal:

PLoS Neglected Tropical Diseases

Year:

2012

Language:

english

File:

PDF, 254 KB

english, 2012

26

A New Look at the Returns and Risks to Pharmaceutical R&D

Grabowski, Henry, Vernon, John

Journal:

Management Science

Year:

1990

Language:

english

File:

PDF, 1.35 MB

english, 1990

27

A New Look at the Returns and Risks to Pharmaceutical R&D

Henry Grabowski and John Vernon

Journal:

Management Science

Year:

1990

Language:

english

File:

PDF, 474 KB

english, 1990

28

Small MultiPiles: Piling Time to Explore Temporal Patterns in Dynamic Networks

Bach, B., Henry-Riche, N., Dwyer, T., Madhyastha, T., Fekete, J-D., Grabowski, T.

Journal:

Computer Graphics Forum

Year:

2015

Language:

english

File:

PDF, 2.73 MB

english, 2015

29

Effective patent life in pharmaceuticals

Grabowski, Henry G., Vernon, John M.

Journal:

International Journal of Technology Management

Year:

2000

Language:

english

File:

PDF, 856 KB

english, 2000

30

Brand Loyalty, Entry, and Price Competition in Pharmaceuticals after the 1984 Drug Act

Grabowski, Henry G., Vernon, John M.

Journal:

The Journal of Law and Economics

Year:

1992

Language:

english

File:

PDF, 1.87 MB

english, 1992

31

Guidance on the use of miglustat for treating patients with type 1 Gaucher disease

Neal J. Weinreb, John A. Barranger, Joel Charrow, Gregory A. Grabowski, Henry J. Mankin, Pramod Mistry

Journal:

American Journal of Hematology

Year:

2005

Language:

english

File:

PDF, 101 KB

english, 2005

32

Gamma-ray studies of 119, 121, 123Sn isomers formed in deep inelastic heavy ion collisions

R.H. Mayer, D.T. Nisius, I.G. Bearden, P. Bhattacharyya, L. Richter, M. Sferrazza, Z.W. Grabowski, P.J. Daly, R. Broda, B. Fornal, I. Ahmad, M.P. Carpenter, R.G. Henry, R.V.F. Janssens, T.L. Khoo, T.

Journal:

Physics Letters B

Year:

1994

Language:

english

File:

PDF, 362 KB

english, 1994

33

“Identical” superdeformed band in 151Dy: further evidence for the pseudospin coupling scheme

D. Nisius, R.V.F. Janssens, P. Fallon, B. Crowell, I. Ahmad, C.W. Beausang, M.P. Carpenter, B. Cederwall, P.J. Daly, M.A. Deleplanque, R.M. Diamond, D. Gassmann, Z.W. Grabowski, R.G. Henry, T.L. Khoo,

Journal:

Physics Letters B

Year:

1995

Language:

english

File:

PDF, 524 KB

english, 1995

34

High level production of human growth hormone in the milk of transgenic mice: the upstream region of the rabbit whey acidic protein (WAP) gene targets transgene expression to the mammary gland

Eve Devinoy, Dominique Thepot, Marie-Georges Stinnakre, Marie-Louise Fontaine, Henri Grabowski, Claudine Puissant, Andrea Pavirani, Louis-Marie Houdebine

Journal:

Transgenic Research

Year:

1994

Language:

english

File:

PDF, 1.73 MB

english, 1994

35

The determinants of pharmaceutical research and development expenditures

Henry Grabowski, John Vernon

Journal:

Journal of Evolutionary Economics

Year:

2000

Language:

english

File:

PDF, 137 KB

english, 2000

36

HOW DID THE 2003 PRESCRIPTION DRUG RE-IMPORTATION BILL PASS THE HOUSE?

OMER GOKCEKUS, MIKE ADAMS, HENRY GRABOWSKI, EDWARD TOWER

Journal:

Economics & Politics

Year:

2006

Language:

english

File:

PDF, 157 KB

english, 2006

37

Follow-on biologics: data exclusivity and the balance between innovation and competition

Grabowski, Henry

Journal:

Nature Reviews Drug Discovery

Year:

2008

Language:

english

File:

PDF, 423 KB

english, 2008

38

Data exclusivity for biologics

Grabowski, Henry, Long, Genia, Mortimer, Richard

Journal:

Nature Reviews Drug Discovery

Year:

2011

Language:

english

File:

PDF, 195 KB

english, 2011

39

Data exclusivity for biologics

Grabowski, Henry, Long, Genia, Mortimer, Richard

Journal:

Nature Reviews Drug Discovery

Year:

2011

File:

PDF, 38 KB

2011

40

A sensitivity analysis of expected profitability of pharmaceutical research and development

Henry Grabowski, John Vernon

Journal:

Managerial and Decision Economics

Year:

1982

Language:

english

File:

PDF, 499 KB

english, 1982

41

Organizational capital and the choice between specialization and diversification

Michael Gort, Henry Grabowski, Robert McGuckin

Journal:

Managerial and Decision Economics

Year:

1985

Language:

english

File:

PDF, 916 KB

english, 1985

42

Pharmacy benefit management, cost-effectiveness analysis and drug formulary decisions

Henry Grabowski, C.Daniel Mullins

Journal:

Social Science & Medicine

Year:

1997

Language:

english

File:

PDF, 1010 KB

english, 1997

43

Introduction and overview

Frank A Sloan, Henry G Grabowski

Journal:

Social Science & Medicine

Year:

1997

Language:

english

File:

PDF, 573 KB

english, 1997

44

Conclusions and implications

Frank A Sloan, Henry G Grabowski

Journal:

Social Science & Medicine

Year:

1997

Language:

english

File:

PDF, 274 KB

english, 1997

45

The economic returns of pediatric clinical trials of antihypertensive drugs

Carissa M. Baker-Smith, Daniel K. Benjamin Jr, Henry G. Grabowski, Elizabeth D. Reid, Barry Mangum, John V. Goldsmith, M. Dianne Murphy, Rex Edwards, Eric L. Eisenstein, Jessica Sun, Robert M. Califf,

Journal:

American Heart Journal

Year:

2008

Language:

english

File:

PDF, 165 KB

english, 2008

46

117. Development of a disease severity scoring system for type I Gaucher disease

Ari Zimran, Maria Cappellini, Timothy Cox, Edward Giannini, Gregory A. Grabowski, Wuh-Liang Hwu, Henry Mankin, Anna Maria Martins, Carolyn Sawyer, Stephan vom Dahl, Neal Weinreb, Michael Yeh

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 45 KB

english, 2008

47

148. A validated disease severity scoring system for gaucher disease type 1

Neal Weinreb, Maria Cappellini, Timothy Cox, Edward Giannini, Gregory Grabowski, Wuh-Liang Hwu, Henry Mankin, Ana Maria Martins, Stephan vom Dahl, Michael Yeh, Ari Zimran

Journal:

Molecular Genetics and Metabolism

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

48

Public policy and innovation: The case of pharmaceuticals

Henry Grabowski

Journal:

Year:

1982

Language:

english

File:

PDF, 2.92 MB

english, 1982

49

Abnormalities in lipoprotein metabolism in Gaucher type 1 disease

Ngoc And Le, Joyce C. Gibson, Ardon Rubinstein, Gregory A. Grabowski, Henry N. Ginsberg

Journal:

Year:

1988

Language:

english

File:

PDF, 637 KB

english, 1988

50

The synthesis of a recombinant protein in milk of transgenic mice

Marie-Georges Stinnakre, Eve Devinoy, Dominique Thépot, Nicole Chêne, Mahasti Bayat-Samardi, Henri Grabowski, Louis-Marie Houdebine

Journal:

Livestock Production Science

Year:

1993

Language:

english

File:

PDF, 209 KB

english, 1993